The field guide

All posts

Explain first, argue second. Every post links back to the primary papers and reporting it draws on.

A scientist examining samples through a microscope in a modern laboratory

Research6 min read

Why xenocortical mice matter for brain medicine

The human brain is locked inside a skull and no animal brain is a good copy of it. That is why schizophrenia, epilepsy and dementia still have so few real treatments.

A digital rendering of a human brain and neural network

Ethics9 min read

The ethics of mice with human brains

The tissue in these mice is immature and the animals were not enhanced. But the ethical questions start long before any mouse gets smarter.

A human hand reaching toward a glowing blue circuit-patterned wall

Ethics, Intelligence8 min read

A half-human mouse brain versus machine AI

ChatGPT learns from oceans of data on silicon. A xenocortical mouse learns from a body, on living neurons grown from human DNA. The comparison says a lot about both.

A researcher's gloved hands holding a white laboratory mouse

Explainers7 min read

What are xenocortical mice? A plain-English guide

In September 2026, researchers at Stanford announced mice whose brains are half human tissue. Here is what the animals actually are, in language that does not need a neuroscience degree.